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Chemistry of Amino acids & Proteins

Learn with Dr. KCN

30 modules

English

Access for 365 days

Unlocking the Secrets of Life: Exploring the Chemistry of Amino Acids & Proteins

Overview

Welcome to the course on "Chemistry of Amino acids & Proteins." In this comprehensive course, we will delve deep into the fascinating world of amino acids and proteins, exploring their structures, functions, and the pivotal roles they play in various biological processes. Whether you're a student, a researcher, or simply interested in understanding the molecular basis of life, this course will provide you with a solid foundation in the field of biochemistry.

This course is specially designed for MBBS, BDS, Nursing, Physiotherapy students

Key Highlights

Understand the structure, properties & classification of amino acids

Exploration of selenocysteine and pyrrolysine as the 21st and 22nd amino acids & non-standard amino acids.

Explanation of the isoelectric point (pI) and its importance

Overview of protein sequencing methods including primary, secondary, tertiary & quaternary structure

Denaturation & Renaturation

The concept of the protein folding, Chaperones along with protein misfolding disorders

What you will learn

Master Amino Acid Fundamentals

Gain a profound understanding of amino acid structure, decipher their chemistry, and classify them according to their properties, including the intriguing 21st and 22nd amino acids.

Explore Non-Standard Amino Acids

Dive into the realm of non-standard amino acids, understanding their roles and significance in biochemical processes.

Demystify Isomerism

Grasp the concept of isomerism in amino acids, discerning the structural variations that impact their functions.

Uncover the Isoelectric Point

Comprehend the concept of the isoelectric point and how it influences amino acid behavior in diverse biochemical contexts.

Master Protein Sequencing concepts

Acquire the concepts behind determination of protein sequencing, a pivotal technique in molecular biology and biochemistry.

Navigate Protein Structures

Explore the hierarchical levels of protein structure, from primary to quaternary, and appreciate how they dictate protein functions.

Decode Protein Folding and Misfolding

Gain insights into the intricacies of protein folding, chaperone-assisted folding, and the consequences of misfolding. Additionally, understand the classification of proteins

Modules

Lecture-1: Introduction of Amino Acids

2 attachments • 7.41 mins

Lecture-1

Preview

Lecture-2: Structures of individual amino acids & Structural classification of amino acids

2 attachments • 18.97 mins

Lecture-2

Quiz

Lecture-3: One Letter Code for Amino acids | How to Remember Single Letter Abbreviations?

2 attachments • 9 mins

Lecture-3

Quiz

Lecture-4: Classification of Amino Acids based on Polarity and Charge on R group

2 attachments • 8.02 mins

Lecture-4

Quiz

Lecture-5: Classification of Amino acids Based on Nutritional Requirement & Metabolic Fate with MNEMONICS

2 attachments • 10.81 mins

Lecture-5

Quiz

Lecture-6: 21st and 22nd Amino acid - Selenocysteine (21st) & Pyrrolysine (22nd)

2 attachments • 23.08 mins

Lecture-6

Preview

Quiz

Lecture-7: Non standard amino acids classification

1 attachment • 12.5 mins

Lecture-7

Lecture-8: Isomerism of Amino acids

1 attachment • 7.66 mins

Lecture-8

Lecture-9: Isoelectric point and zwitterions _ Amphoteric Nature of Amino acids _ Calculate isoelectric pH

1 attachment • 28.34 mins

Lecture-9

Lecture-10: 10. How to calculate number of amino acid residue in protein from its molecular weight

1 attachment • 10.5 mins

Lecture-10

Lecture-11: Determination of Amino Acid Composition

1 attachment • 17.3 mins

Lecture-11

Lecture-12: Protein Sequencing (Step 1 & 2) _ Other steps continued in next video

1 attachment • 13.58 mins

Lecture-12

Lecture-13: Protein Sequencing (Step 3) _ Sanger & Edman Sequencing _ Determination of N terminal Amino acid

1 attachment • 21.52 mins

Lecture-13

Lecture-14: Protein Sequencing (Step 4) _ Identification of C Terminal amino acid _ Hydrazinolysis

1 attachment • 10.88 mins

Lecture-14

Lecture-15: Protein Sequencing (Step 5) _ Cleavage of peptide into overlapping smaller fragments

1 attachment • 11.66 mins

Lecture-15

Lecture-16: Primary Structure of Protein

1 attachment • 14.55 mins

Lecture-16

Lecture-17: Secondary structure of proteins _ Alpha helix

1 attachment • 19.53 mins

Lecture-17

Lecture-18: Beta Pleated Sheet _ Secondary Structure of Proteins

1 attachment • 14.13 mins

Lecture-18

Lecture-19: Beta bend, Non Repetitive & Supersecondary (Motif) Str _ Secondary structure

1 attachment • 12.46 mins

Lecture-19

Lecture-20: Tertiary structure of proteins

1 attachment • 16.75 mins

Lecture-20

Lecture-21: Quaternary Structure of Proteins

1 attachment • 8.9 mins

Lecture-21

Lecture-22: Denaturation and Renaturation of Proteins _ Ribonuclease A

1 attachment • 14.37 mins

Lecture-22

Lecture-23: Protein folding, Chaperones & Enzymes

1 attachment • 16.57 mins

Lecture-23

Lecture-24: HSP-70 & HSP-40 Chaperone _ Protein Folding

1 attachment • 8.56 mins

Lecture-24

Lecture-25: GroEL - GroES System _ HSP 60 - HSP 10 System _ Chaperonin Assisted Protein Folding

1 attachment • 6.73 mins

Lecture-25

Lecture-26: Molecular Chaperones

1 attachment • 9.74 mins

Lecture-26

Lecture-27: Protein Misfolding and Disorders _ Alzheimer _ Prion disease

1 attachment • 13.68 mins

Lecture-27

Lecture-28: Classification of Proteins [Part-1] _ Based on Functions, Chemical nature (Solubility) & Shape

1 attachment • 24.14 mins

Lecture-28

Lecture-29: Classification of Proteins [Part-2] _ Derived Proteins

1 attachment • 8.93 mins

Lecture-29

Lecture-30:

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Absolutely! we are committed to providing an engaging and interactive learning experience. You will have opportunities to interact with them through our community. Take full advantage to enhance your understanding and gain insights directly from the expert.

About the creator

About the creator

Learn with Dr. KCN

Elevate your learning experience with Dr. KCN, a passionate expert in Medical Biochemistry having vast experience of teaching Medical Biochemistry of more than 14 years in one of the reputed medical college in India. Educational qualifications of Dr. KCN is MBBS, MD (Biochemistry). 

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